Superficial Cortical Venous Network

An extensive network of interconnected veins running within the sulci, highly variable in size, route, and drainage pathway subserve venous egress of the cerebral convexity. These veins typically drain the cortex, u-fibers, and some underlying deep white matter.  Most of hemispheric white matter drains into the deep veins (such as longitudinal caudate veins and lateral atrial veins, and then into the internal cerebral vein). Some of the more constantly noted channels have names.  The extent of anastomotic connections between these veins determines the depth of system “reserve” should some portion of the network become dysfunctional.  For example, a surgeon can divide a temporal cortical vein in presence of anastomoses to the frontal or parietal network.  A large isolated drainage channel cannot be sacficed without substantial risk of a venous infarction.  The same goes for deep venous thrombosis, having some bearing on presence and extent of hemorrhagic infarction depending on level of collateral support. 

Various names exist for the anastomotic veins of the convexity, however even when no functionally competent anastomosis exists the veins usually keep their names.  The vein of Trolard is a large posterior frontal vein (usually in the post-central sulcus) draining into the superior sagittal sinus.  The Rolando is a named vein posterior to Trolard draining the parietal lobe. The Labbe is the largest vein draining the temporal convexity towards the transverse or sigmoid sinus.  The superficial sylvian vein collects tributaries from the region of the opercula and adjacent cortex and has a variable pattern of drainage.  Variability is the rule.  All sorts of percentages of dominance are found in venerable texts.  The bottom line is that anything from a balanced network of interconnected Trolard, Labbe, and Sylvian veins to essentially separate drainage, to dominance of one channel at expense of others is illustrated below. The key is to understand which way venous blood is leaving the brain, and what constraints this may impose on a potential surgical approach or endovascular embolization.  

Below are some illustrations of variable superficial drainage patterns. 

Balanced pattern.  The Trolard, Labbe, and Sylvian veins are interconnected in the region of the posterior sylivan fissure.  Any one of these veins can be sacrificed with very low risk of venous infarction. Also notice a sigmoid emissary vein (unmarked).

White=Trolard. Orange=Superficial Sylvian Vein draining into sphenoparietal sinus (red) and into the pterygopalatine venous plexus (pink). Purple=Labbe.  Notice variant drainage of the basal vein (blue) into the superior petrosal sinus (light blue).  Midline shift is evident on AP views (green) 

Another illustration of the balanced pattern with a somewhat more dominant Trolard.

Trolard=dark blue. Labbe=green. Superficial sylivan vein/sphenoparietal sinus=yellow. Notice that Trolard-Labbe anastomosis is much lower over temporal convexity than in the previous figure. Cavernous sinus=red. Basal vein=black. Galen=red. Internal Cerebral vein=pink. Thalamostriate vein=light blue. Anterior caudate vein=double green.

Perfectly balanced pattern

Equal sized Trolard (purple), Labbe (blue), and Superficial Sylivan (pink) veins, all connected to each other (white arrow). 

Another example of collateral connections between the Labbe (white) and Superficial Sylvian (blue) veins. Also notice full extent of the basal vein (purple, black, pink arrows) from the cavernous sinus to the Galen.

Here is an example of an anastomosis between the Labbe and a frontal vein, draining into the proximal superior sagittal sinus (no labels)

Labbe to anterior frontal vein collateral

Dominant Labbe Pattern. As you can seen, the Labbe is draining a huge swath of the cortex, capturing sylivan territory with a hypoplastic sphenoparietal sinus.  Many frontoparietal cortical veins empy into the Superior Sagittal Sinus without connection to the Labbe.  This is the kind of Labbe you cannot sacrifice.  Also, lack of anstomoses imposes a relative inflexibility to the system with relatively little “reseve” should one of these channels close. Various books report that a dominant Labbe is more common on the left (dominant temporal lobe), whereas the trolard is on the right.  That is certainly true, except when its not. 

Labbe=dark blue. Inferior temporal vein=beige. Inferior sagittal sinus=light blue.  Straight sinus=black.  Basal vein=red. Internal Cerebral Vein=green.  Notice dominance of drainage to the sigmoid sinus system with no visualization of the sphenoparietal sinus or cavernous sinus.  The basal vein drains exclusively posterior.  This patient would be very unlikely to tolerate sigmoid sinus or straight sinus thrombosis.

 Another Dominant Labbe patern on the left. Labbe capturing sylvian vein territory.

Sylivan veins=purple. Labbe=whte. Basal vein=pink. Deep middle cerebral vein=light blue.

Pseudo-Labbe Dominance.  Giant vein, not Labbe but temporo-occipital vein collecting sylvian and large swaths of convexity territory in a patient with underdeveloped cavernous and petrosal sinuses. Notice how this drainage affects the transverse sinus, which is hypoplastic proximal to the temporo-occipital vein.

Light Blue=sylvian network.  Dark blue = temporooccipital vein.  Orange = Labbe. White=left transverse sinus.  Green= right transverse sinus.  Purple=inferior sagittal sinus.  Pink=dural sinus channel separate from the straight sinus.  Red=Galen.  Black = straight sinus.

Dominant Rolando

The vein of Rolando (the giant one in the center of the image pair) is situated, appropriately in the Rolandic region, anterior to the Trolard.  This extreme example of Rolando dominance of the entire hemisphere convexity illustrates the extent to which a single vein can occasionally assume control of the lateral surface territory.  This pattern of very limited flexibility carries relatively very high risk of venous infarction should any misfortune (DVT, iatrogenic injury, etc) befall the dominant vein.  On a personal note, I think that these extremes are more likely to be associated with additional vascular abnormalties or variants.  This patient has a cavernous angioma with an associated DVA in the posterior right temporal lobe (not shown)

Dominant Superficial Sylvian Veins

The superficial sylvian veins outline the sylvian fissure, coursing inferiorly to mark the anterior aspect of the temporal lobe, and typically draining either into the cavernous sinus, paracavernous sinus (or cavernous sinus lateral complartment, if you wish), or the superior petrosal sinus. Here is an example of markedly dominant superficial sylvian veins (blue), in this case emptying into the cavernous sinus (white)

Superficial Sylvian Veins

As is often the case, when Sylvian veins are dominant, several venous channels run in parallel to converge on the sinus, as is well-illustrated above.  This arrangement is not commonly seen elsewhere — one might expect these veins to form a common trunk.  It also brings up the somewhat obscure but embryologically important discussion regarding the existence of the “sphenoparietal” sinus.  There are no less than 4 separate veins here so at least some are draining into the cavernous sinus directly — perhaps all of them.  See “Cavernous Sinus” page for more on this exciting topic.

Here is a stereo image of the above. Isn’t stereo cool?

Superficial Sylvian Veins

Dominant Superficial Sylvian Vein Pattern:  The Superficial Sylvian vein is dominant, draining into a large superior petrosal sinus via the inferior temporal vein. The cavernous sinus drainage pathway is hypoplastic.

Blue Circle=tumor blush.  The superficial sylivan vein is prominent within the circle and extends over the temporal lobe towards the superior petrosal sinus (dark blue arrow).  Labbe=black. No trolard is seen, various superior cortical veins drain into the SSS. Basal vein=light blue, dominant posterior drainage.  Very nice demonstration of the deep venous system tributaries.  Anterior Septal vein=bright green, capturing territory of hypoplastic anterior cerebral vein.  The inferior sagittal sinus is absent.  Thalamostriate vein with large longitudinal caudate vein=yellow.  Direct lateral vein=pink.  Posterior caudate/splenial veins=brown. 

Discontinuous pattern with cavernous sinus drainage of the sylivan vein.  Unlike the above example, the sylivan vein drains into the sphenoparietal sinus and subsequently into the cavernous sinus, as is usual.  A giant recurrent paraophthalmic segment aneurysm is partially filled with coils.

Sylivan Tributaries over frontotemporal operculum=Dark blue.  Sylivan vein/sphenoparietal sinus=light blue. Cavernous sinus=purple. Inferior petrosal sinus=orange.  Ovale drainage of the cavernous sinus=white.  Pterygopalatine fossa veins=red.  Labbe=pink.  Thalamostriate=yellow.  ICV=black. 

Dominant sylvian vein egress sacrifice

In this patient with a large right temporal lobe hematoma from a surface/pial AVM rupture, the Sylivan vein consistitutes primary drainage of the temporal lovbe and operculum via the sphenoparietal sinus into the cavernous sinus.  No effective Labbe or Trolard type collateral to the sylvian region exists. (LEFT)  The AVM was embolized and resected.  The sphenoparietal sinus was sacrificed during surgery.  Postoperative angiogram (RIGHT) demonstrates marked congestion of the surface hemispheric veins which via multiple small collateral pathways are straining to drain the sylivan vein territory into the superior sagittal sinus.   There was no hemorrhage.

Superficial sylvian vein = light blue.  Sphenoparietal sinus = dark blue. Cavernous sinus = orange.  Inferior petrosal sinus = black.  Pterygopalatine venous plexus = green. Mass = blue oval.  Mass effect on sylivan veins=pink. Congested small veins = red. 

Sylvian-Labbe Collateral Pattern s/p sigmoid sinus occlusion:

MRI showing a meningioma filling up the right sigmoid sinus.  Angio confirms sinus occlusion.  The Labbe is rerouted into the sylvian network, which due to hypoplasia of the cavernous sinus outflow drains into a very capacious basal vein.

Red=occluded Labbe Segment. Dark Blue=labbe; Light blue=superficial sylvian vein; black=inferior parietal vein; yellow=deep sylvian vein; purple=basal vein; white=anterior septal vein; pink=thalamostriate vein; green=longitudinal caudate tributaries of the thalamostriate vein; brown=internal cerebral vein; orange=meningioma occluding right transverse/sigmoid sinus 

Dominant Trolard Pattern.  The Trolard is dominant with anastomosis to a smaller Labbe. This Trolard can probably be sacrificed.  Notice also a somewhat strange pattern of inferior frontal venous drainange coming over the anterior portion of the SSS to empty contralaterally.

Trolard=yellow.  Notice mass effect from tumoral edema/infiltration on the inferior portion of the Trolard (red). Mass effect on the thalamostriate vein (orange).  Frontal vein with anomalous drainge = dark blue.  Superior petrosal sinus=pink.  Notice a very large occipital sinus also=purple.

Dominant Rolando with connection to the deep middle cerebral vein.  Numerous anastomoses between “superficial” and “deep” system make this classification somewhat misleading.   Its important to keep this in mind.  Here, a large trolard (red) is continuous inferiorely with the deep middle cerebral vein (the most inferior red arrow) draining into the cavernous sinus.

Rolando=red.  Deep Middle Cerebral vein=black. Cavernous sinus=white.  Anastomotic vein between SSS and ISS=yellow. Basal Vein=pink. Superior Petrosal sinus=Dark blue.  Inferior petrosal sinus=light blue. Tumor blush=blue circle

Anterior Frontal Veins — beware the first 1/3rd of the superior sagittal sinus

There is an old rule in neurosurgery, which says that taking (occluding) the first /anterior third of the superior sagittal sinus is generally a safe thing to do.  That is certainly true, and the reason for this is that veins are, again, like rivers — the river is as large as the sum total of its tributaries.  Because the early anterior tributaries which form the SSS are generally small and few in number, the SSS itself is small anteriorely, and taking it will be fine because the tributary veins will find another way to drain.  The important part is to remember the exceptions to the rule, which is basically when there is a large, dominant frontal vein present. This vein is easiest to see on an angiogram, like this one (blue arrows), although trained eyes can pick up the same on an MR or CT with contrast study.

large frontal vein

One does have to be careful with TOF MRV images — I think they have lots of problems in general, and in this case this large vein is barely visible — the purple arrow points to the SOV vein and is a fakeout.

frontal veins

On the next TOF MRV image, obtained on a TrioTim 3T magnet, the vein is seen much better than on the Skyra study

mrv frontal vein

I find it is much better to look at veins on a post-contrast T1 study (of course, one has to be careful about precontrast T1 hyperintensity, etc. However, with good proficiency, postcontrast T1 is better than TOF MRV in most cases).  This is what it looks like

frontal veins

As often the case, there is a dominance of anterior frontal veins on the left also, however joining the SSS a bit more posteriorly (white arrows).  A large Labbe (yellow) is also present.

frontal veins

MRI tracing same veins on the left side

mrv frontal vein

Dural Sinuses — much more on this important topic on the Venous Sinuses Page

Although the majority of superficial veins empty directly into the major named venous sinuses (Superior Sagittal, transverse, straight  [see Dural Venous Sinuses page]), the occasional exception whereby the vein joins an unnamed dural venous sinus channel first, reminds us of some relevant embryology and keeps the informed surgeon on his/her toes.  During early development, venous channels preferentially form at the confluence of dural sheets (such as falx and upper dura for the superior sagittal sinus, or the tentorium and lateral dura for the transverse sinus).  However, short dural channels outside of these confluences are often present.  These can be recognized with a trained eye as being somewhat broader along the dural surface and flatter in a tangential plane to the dural sheet within which they are located.  Longer ones are progressively less common, but still can be seen with regularity.  Below is an example of a parieto-occipital dural sinus (white) which collects a somewhat peculiar duo of surface veins (light blue).  The transition from cortical vein to dural sinus is marked by the purple arrow.  It is typical to see dural sinuses associated with larger, more dominant surface veins, probably because dural sinus is not a favored embryologic structure, and in order for it to persist the flow demand must be somewhat high.  Notice also bilateral transverse/sigmoid sinus stenoses in this patient with pulsatile tinnitus and intracranial hypertension.

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Stereo views of the same arrangement, several years later.

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A stent (yellow) has been placed into the dominant sigmoid sinus.  While pulsatile tinnitus was cured, the headaches which initially improved then recurred, and a shunt was eventually placed (purple, white).  Notice recurrence of narrowing (black) just distal to the stent, as is typical in such failed stent cases.

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Advanced venous imaging

Sometimes, its good to get an angio when you are at a loss about something that might be vascular — bleeding, for example.  Here is a young man with spontaneous left temporal lobe hemorrhage.  MRI shows no evidence of AVM, aneurysm, or any other problem.  In our book, this needs an angio

MRI (hemoflash and T2, and CT images of left temporal hemorrhage).  Note to radiologists — please don’t ask to see the whole study — there is nothing suspicious there, believe me.

Angio of the same patient — what is the diagnosis?

Cerebral venous thrombosis.  Isolated thrombosis of the inferior temporal vein/vein of Labbe.  Notice irregular and thinned appearance of inferior temporal gyrus vein (dark blue arrows), compared with the larger caliber of the same vein anteriorly (purple) and posteriorly (light blue), which is the vein of Labbe.  Other signs are:1) There are no normal veins seen draining the temporal convexity — this cannot possibly be normal.  Deep sylvian veins and striate veins are there (unlabeled, see venous system for clarification)  If you do enough angio, you will recognize that this appearance is very abnormal. Every other lobe has juicy veins, for example.2) There is evidence of temporal lobe congestion, which is somewhat subtle, but present — in the inferior and superior temporal regions.  The middle “layer” of the temporal lobe is hypovascular — corresponding to location of the clot — its a hyperemia-clot-hyperemia sandwich.

As usual, cerebral venous thrombosis can be an elusive diagnosis — especially if the sinuses are not involved.  But it certainly happens, and certainly more often than is known about.

stereo pair of the same patient, can’t resist having one. Notice hyperemia adjacent to congested inferior temporal lobe vein, and clot-related lucency above it.

Venous Thrombosis Case 2

This patient with Sickle Cell Disease presented with headache.  CT identified subarachnoid hemorrhage over the convexity (red arrows).  The subtle hyperdensity adjacent to the left inner table was not appreciated initially (pink arrows).

 

The patient was referred directly for angiography to look for the cause of subarachnoid hemorrhage.  Frontal and lateral projection digital subtraction angiographic views of the left ICA injection, in venous phase, demonstrate abrupt cutoff (pink arrows) of the vein of Labbe.  ”Tram-track” sign of filling defect in the vein is acually seen on the lateral image (yellow arrow).  The venous sinuses are fully patent.

Subsequently obtained contrast MRI demonstrates nicely the hyperintense thrombus on sagittal T1-weighted imaging, and the intraluminal thrombus is seen on post-contrast T1-weighted images (yellow arrows). Again, the sinuses are patent (green arrows).  Patients with sickle cell disease are, of course, at major risk for sickling, leading to both arterial and venous thrombosis.

Sturge-Weber Syndrome, a.k.a. Encephalotrigeminal Angiomatosis

SWS is part of a family of neurocutaneous disorders, characterized by abnormalities of ecto- and endoderm.  The cutaneous part is a port wine stain (in CN V distribution).  The brain part is described below.  About 1/3 of patients only have the skin part, 1/3 have only brain, and 1/3 both — no rocket science here.  The cause is unknown.  There are many sources of excellent information on the Web, but I am afraid that most individuals do not appreciate the underlying vascular issues of SWS in the brain, which is illustrated angiographically below.
Cerebral manifestations of SWS appear to stem from abnormal development of the venous system — particularly surface veins.  The halmark of venous imaging is absence of superficial veins (including basal vein, which is only deep as far as the surgeon is concerned, being in fact a superficial vein on the undersurface).  As a result, venous drainage is impaired, with secondary tremendous venous congestion.  The congestion leads to engorgement of countless small veins thoroughout the parenchyma, and particularly on the gyral surface.  This produces the characteristic gyral enhancement seen on MRI, and venous congestion that is better appreciated angiographically.  The characteristic gyral calcifications probably result from chronic venous congestion.
This is a young patient with intractable seizures.

 

x-ray views of the skull, showing extensive gyral calcifications on background of cererbral atrophy.

Various MRI sequences highlighting atrophy, calcifications, and gyral pattern of enhancement (top row). Notice absence of left basal vein, and most surface convexity veins.

TOF and venovibe images; almost normal venous pattern on the right, and gyral enhancement (arrows) as well as transosseous venous channels on the left.

 

Stereoscopic views (top) and labeled image (bottom) of quasi-normal right ICA injection; convexity surface veins are present.  A tremendous, tortuous basal vein (blue arrows) is working overtime. Some of its lenticulostirate tributaries, pathologically enlarged (why?) are labeled yellow.  The convexity drainage is dominated by superficial sylvian veins (purple).  What vein is missing?

The same R ICA injection, in AP projection.  Notice multiple venous channels draining the anterior frontal lobe over the left convexity.  They are intra-osseous veins, and well seen on the venovibe MRI image of the left hemisphere (no labels on that one).  The basal vein is blue, and its deep tributaries are yellow. The internal cerebral vein is missing.  Its territory is drained by the basal vein.  I don’t understand the developmental physiology of why it is missing.

This is a lateral view of the abnormal hemishere, left ICA injection, in late venous phase.  The image is characterized by near-complete absence of surface veins and tremendous venous congestion.  Appreciate how gyral calcifications, seen on the x-ray image above, are greatest over the areas with least superficial venous drainage. Over the frontal lobe, where several surface veins (pink) have developed, the calcifications are less pronounced.  The basal vein is labeled in blue.  Why is the basal vein seen?


 

AP views of left ICA injection.  The basal vein seen on the lateral study belongs on the right side.  It is draining both hemispheres, hense its large size.  Left-sided tributaries (green arrows) reach the right side accross the posterior communcating vein (interpeduncular vein) which connects the two basal veins in front of the brainstem.


The disease is not limited to anterior circulation.  Even more tremendous venous congestion (blue outline), with no effective surface veins, afflicts the left cerebellum, brainstem, and posterior cerebral artery territory, in stark contrast with normal right side.  The brainstem drains almost exclusively via a large lateral mesencephalic vein (red), into the petrosal vein (beige), and ultimately into the superior petrosal sinus (white).  An anterior mesencephalic vein (green) points straight up from medial aspect of lateral mesencephalic vein.

 

Lateral view of the same left vert injection.
Venous Enigmas
One appearance that has puzzled our group, and i am sure has been observed by others, is a kind of corkscrew-like tortuousity of surface convexity veins.  I do not know the cause for it, though it seems that it is observed perhaps more frequently in patients with a history of increased intracranial pressure (such as SAH patients).  If you know what it is, please tell me.
Stereoscopic views of tortuous surface convexity veins in a patient with a cryptogenic posterior medial frontal convexity hematoma.  Did a vein rupture?